Intra-Uterine Devices (IUDs)

Subject: Zoology

Difficulty Level: Easy
Intra-Uterine Devices (IUDs)
non-medicated
Copper-Releasing
Hormone-Releasing

Updated by: Arabinda Naik

Answer:

Intra-Uterine Devices (IUDs)

Intra-Uterine Devices (IUDs) are a popular and effective contraceptive method used by women to delay or prevent pregnancy. These devices are inserted into the uterus through the vagina by a trained healthcare professional, such as a doctor or nurse. IUDs are one of the most widely accepted contraception methods in India due to their long-lasting and reliable nature.

4.8.5.1 Types of IUDs

4.8.5.2 non-medicated

Example: Lippes's loop.                                                                                                                                                              These devices do not release any medication or hormones but act as a physical barrier in the uterus.

4.8.5.3 Copper-Releasing

Examples: Cu-T, Cu-7, Multiload 375.                                                                                                                                      These IUDs release copper ions, which help suppress sperm motility and their fertilizing capacity. Copper increases phagocytosis of sperm within the uterus.

4.8.5.4 Hormone-Releasing

Examples: Progestasert, LNG-20.                                                                                                                                                  These IUDs release hormones, such as progesterone or levonorgestrel, which make the uterus unsuitable for implantation and disrupt sperm function by releasing toxic cytokines.

4.8.5.5 Mechanism of Action

Copper IUDs: Release copper ions that enhance sperm phagocytosis within the uterus. This reduces sperm mobility and fertilization capacity. Copper release from the device occurs at a rate of about 50 mg/day and is effective for 3-5 years.

Hormone-releasing IUDs: These devices slowly release hormones that alter the uterine environment, making it hostile to sperm and preventing embryo implantation.

4.8.5.6 Maintenance and Lifespan

IUDs need to be replaced every 3-5 years when the effectiveness of copper release decreases due to calcium deposition on the device.

Questions you should look

Explain different Intra-Uterine Devices (IUDs)
Uterus
Write short notes on Menstrual cycle
Write short note on Menstrual phase
Write notes on gastrulation